Pizza Meatloaf

If you’ve grown tired of making traditional meatloaf, Pizza Meatloaf is the easy comfort food recipe that you need to spice things up. Chop up pepperoni, or any of your favorite pizza toppings, to mix into this homemade meatloaf with some melted mozzarella cheese!

Pizza stuffed meatloaf with mozzarella cheese.

Pizza Meatloaf – Two Comfort Foods in One!

You’ve had meatloaf, and you’ve had pizza… but have you tried them together? No? This recipe might just be lifechanging, then. Pizza Meatloaf is all of the tastiness of cheesy, pepperoni pizza, packed into a loaf of juicy ground beef instead of a crust!

Usually when I announce that we’re having meatloaf for dinner, my kids are less than thrilled. However, when the word pizza is thrown in, the atmosphere changes dramatically. (Pepperoni and gooey mozzarella cheese are the best defense against pick-eating tendencies, in case you were wondering.) Enjoy this super simple comfort food dinner, and feel free to customize what you add in!

Ingredients for pizza meatloaf.

Recipe Ingredients

As is usually true for most comfort food recipes, the ingredients list for this homemade meatloaf is pretty short:

  • Pepperoni: If you would rather use another meat, like bacon, feel free!
  • Ground Beef: I prefer to use lean ground beef for this recipe.
  • Egg: Will bind the meat together and add moisture.
  • Cheese: I like to use both mozzarella and ricotta cheese in this meatloaf.
  • Seasoning: You’ll need thyme, garlic powder, oregano, crushed red pepper, and salt.
  • Breadcrumbs: Italian breadcrumbs work really well, as do Panko breadcrumbs.
  • Sauce: Use your favorite tomato sauce (I like Homestyle Ragu sauce*) or pizza sauce.

*I LOVE the new Homestyle Ragu sauces…they are thick and taste super fresh. I would even use this in place of pizza sauce on a homemade pie! There are no artificial flavors, no high fructose corn syrup, and the flavor is super bold. I really, really love it. I found it at my local Stop & Shop.

Pizza meatloaf on a cutting board.

How to Make Pizza Meatloaf

If you’ve got busy school/work nights, Pizza Meatloaf is a great dinnertime solution. It only takes about 15 minutes to put together, and then you just have to let it bake, which means you can go do other things while you wait, if need be!

Prepare: Preheat the oven to 350°F. Lightly coat a 9×13 baking dish with nonstick spray and set aside.

Combine Ingredients: In a large bowl using your hands combine pepperoni, ground beef, egg, ricotta cheese, thyme, garlic powder, oregano, breadcrumbs, salt, and red pepper.

Layer the Meatloaf: Divide the mixture in half and place half of it in the prepared pan, forming into a loaf shape, creating a shallow well. Place the cheese slices in the well of the ground beef mixture. Top the cheese with the remaining meat mixture, making sure to seal the cheese inside, so it doesn’t leak out.

Add Sauce & Bake: Spread half of the Ragu Sauce on top of the meatloaf and bake for 45 minutes.

Meatloaf with sauce being poured on top of it.

Bake Again: Remove the meatloaf from the oven, spread the remaining sauce on top and bake for an additional 15 minutes. Serve warm.

Pizza Meatloaf covered in sauce.

Tips for Success

And that’s it! Simple, right? Here are some extra tips so you can make sure you get the best results with your meatloaf:

  • Ground Beef Substitutes: Italian sausage can be mixed in with your ground beef for extra flavor. Ground turkey is also good as a meatloaf base if you don’t want to use beef.
  • Mozzarella Substitute: Mozzarella is the best cheese to use because it melts so well, but provolone will also work in a pinch.
  • Other Add-Ins: Onions, spinach, mushrooms, peppers, and any other pizza toppings you can think of, will all taste amazing in this meatloaf!
  • How to Know If the Meatloaf is Done: Stick a meat thermometer in the center, or thickest part, of the meatloaf and make sure it reads 165°F. Try not to overcook it – dry meatloaf is not an experience you want to have!
Pizza meatloaf with sauce in a pan.

Serving Suggestions

Wondering what to serve with Pizza Meatloaf? Here are a couple of ideas:

  • Garlic Bread: Everybody knows that garlic bread (or Garlic Knots) goes perfectly with pizza, so why not pizza meatloaf?
  • Salad: For a lighter option, a green salad is a good idea – and if you have time try this Homemade Ranch Dressing with it!
  • Roasted Vegetables: Asparagus, broccoli, etc. – whatever your go-to veggies are.

How to Store and Reheat Leftovers

Leftovers (if you’ve got ‘em!) can be refrigerated in an airtight container for 2-3 days. When you want to reheat the meatloaf, bake in the oven at 350°F again until the desired temperature is reached, or simply microwave.

Can I Freeze Extras?

Yes! Store extras in an airtight container, or wrap them in aluminum foil and seal them in a freezer bag. Make sure to eat the leftovers within 3 months, and thaw them in the fridge overnight before reheating.

Pizza meatloaf filled with mozzarella cheese.
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Pizza Meatloaf

  • Author: Shelly
  • Prep Time Prep Time: 15 mins
  • Cook Time Cook Time: 1 hour
  • Total Time Total Time: 1 hour 15 mins
  • Yield Yield: serves 6 1x
  • Category Category: Dinner
  • Method Method: Oven
  • Cuisine Cuisine: American

Description:

If you’ve grown tired of making traditional meatloaf, Pizza Meatloaf is the easy comfort food recipe that you need to spice things up. Chop up pepperoni or any of your favorite pizza toppings to mix in with some melted mozzarella cheese!


Ingredients:

  • 6 ounces pepperoni chopped
  • 2 lbs lean ground beef
  • 1 egg
  • 1 1/2 cups ricotta cheese
  • 1 teaspoon thyme
  • 1 teaspoon garlic powder
  • 1 teaspoon oregano
  • 1/2 cup Italian breadcrumbs
  • 1/2 teaspoon salt
  • 1/2 teaspoon crushed red pepper
  • 8 ounces sliced mozzarella
  • 1 cup Homestyle Ragu sauce

Instructions

  1. Preheat the oven to 350°F. Lightly coat a 9×13 baking dish with nonstick spray and set aside.
  2. In a large bowl using your hands combine pepperoni, ground beef, egg, ricotta cheese, thyme, garlic powder, oregano, breadcrumbs, salt, and red pepper.
  3. Divide the mixture in half and place half of it in the prepared pan, forming into a loaf shape, creating a shallow well. Place the cheese slices in the well of the ground beef mixture. Top the cheese with the remaining meat mixture, making sure to seal the cheese inside, so it doesn’t leak out.
  4. Spread half of the Ragu Sauce on top of the meatloaf and bake for 45 minutes.
  5. Remove the meatloaf from the oven, spread the remaining sauce on top and bake for an additional 15 minutes.
  6. Serve warm

Keywords:: pizza meatloaf, pizza meatloaf recipe, pizza stuffed meatloaf, easy comfort food recipes, ground beef meatloaf recipe

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*Sponsored post by Lunchbox. All opinions are my own.

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Hi! I’m Shelly and I’m an addict. Of the buttercream sort. I started this site a few years ago as a way to justify my sugary, buttery obsession with desserts. It has worked out well for me so far, because as it turns out you guys all love sugary, buttery desserts too! It feels good to know you're not alone, doesn’t it?

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Beth R.
August 3, 2016 11:26 am

Made this last night for dinner…OH MY GOODNESS!! Why had I never thought of this before?? Because rock star Shelly did!! You have yet to let me down with any of your recipes! Thanks for another tasty one!! I think next time I will replace a .5 lb of beef with Italian Sausage, but everything else exactly the same!!

May 2, 2016 9:53 am

Pizza + Meatloaf = my dinner dreams come true! I can’t wait to try this one, Shelly!

Yum! This is a great way to get kids excited about meatloaf!

Sharon
April 29, 2016 10:03 pm

I made this tonight for dinner and everyone loved it. The only thing I changed was the garlic powder. I only used 1/2 tsp. since 1 tsp. seemed like a bit too much. It was really good and will be making again. Only suggestion I would make would be to put the meatloaf on a rack first, since a lot of grease accumulates on the bottom of the pan.

April 27, 2016 8:44 am

Oh my gosh. The cheese. The meat. Perfect weeknight meal!

April 27, 2016 7:51 am

It’s been too long since we’ve enjoyed meatloaf around here. LOVE this pizza twist!!

April 25, 2016 3:05 pm

This combo is completely genius!!! So making for dinner this week!

Teija
April 25, 2016 2:18 pm

Another one to add to my list 😉 I think I made 5 from your cookbook this weekend and another three on tap. A friend picked me up some Gruyere to make the grilled cheese sandwiches this week. The chocolate chip caramel bars are delicious and have been a huge hit both at home and work. Can’t wait to bake up the Lemmy’s tonight! This pizza meatloaf is definitely going on the menu – soon!

April 25, 2016 9:08 am

Pizza Meatloaf?! Oh yah, this is so happening for dinner 🙂

April 25, 2016 8:26 am

Two delicious, comfort foods in one? This is the ULTIMATE and I need it for all the dinners for the rest of my life. Pinned!

April 25, 2016 8:20 am

When I first saw this recipe, I thought it was a pizza flavoured substitute for all pizza fans who are on low-carb diet, and actually can not have it. In fact this recipe serves both – meat and pizza lovers.

April 25, 2016 8:14 am

Definitely adding this to the “to try” list. We all love meatloaf and this looks amazing!! Isn’t Ragu sauce a miracle? I always have a jar in the pantry.

Shelly Hi! I’m Shelly and I’m an addict. Of the buttercream sort. I started this site a few years ago as a way to justify my sugary, buttery obsession with desserts. It has worked out well for me so far, because as it turns out you guys all love sugary, buttery desserts too! It feels good to know you're not alone, doesn’t it?

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